When five animal rights activists from the âStop Green Hillâ group broke into a neuroscience laboratory at the University of Milan last week, they had no idea exactly what was lurking in the cages. Still, the quintet set about changing the labels that identified more than 800 mice and rabbits that had been genetically modified to mimic psychiatric disorders like Alzheimerâs, autism, and schizophrenia, as well as central nervous system maladies like Parkinsonâs disease. The research center was part of a multimillion dollar project funded by a vast array of international charities and institutions looking for cures for the diseases.

The activists, two of whom chained themselves by their necks to the door to prohibit security officials from entering out of fear of breaking their necks, occupied the facility for 12 hours before negotiating a safe getaway with a cache of around 100 lab mice and a rabbit. They released scores of critters, many of whom are still roaming and running around the universityâs animal labs. Other animals have been found dead under cabinets and drain pipes.
Stop Green Hill, which was formed in 2001 to stop the activities of a dog-breeding facility in Brescia, then posted video of their escapades. Many of the mice they took were ânude,â meaning their genetic profiles had been stripped in preparation for the introduction of disease genes. âIt will take at least a year to build up the colonies we had of mouse models of different psychiatric diseases,â Michela Matteoli, the labâs director, told The Daily Beast. âMore than two dozen lines of diseased mice have now been destroyed.â
The activists have not been arrested, and they have promised to continue to protest against the use of animals in laboratory work. On April 28, thousands of animal rights activists are expected to descend on Rome for a national âAnimal Liberation Dayâ protest in the historical center near Parliament. They promise to release hundreds of animals, including lab rats confiscated from other research facilities that have been kept at the groupâs headquarters. The call to action on the organizersâ website asks people to speak for the animals: âEach of us is the voice of those captive animals and we purport their liberation. Each of us must be a glimmer of knowledge to those around us, a spark for change.â
But more likely, the groupsâ efforts mean that even more animals will be sacrificed for science. The Milan researchers are bound by multi-year contracts to enable their work. That means hundreds more mice will be bred to replace those lost in last weekâs fiasco at the facilities. Matteoli says that they are constantly looking for other ways to do their work that does not involve animals, but it is virtually impossible to understand the diseases using Petri dishes alone. âWe can do a lot of research before we use the animals,â she says. âBut at a certain point we need a living creature to test what happens when certain proteins are absent.â
In an open letter the university research team scolded the activists for wasting thousands of euros in grant money and hindering the progress of finding ways to treat and cure diseases. âSaturdayâs incident creates an extraordinarily serious precedent. It is undeniable that animal experimentation is a delicate ethical issue,â the letter reads. âHowever, it is equally undeniable that it is only by using laboratory animals that we have been able to make the medical advances and therapeutic progress of the past, and that this will also be necessary for future developments.â
Stop Green Hill says they wonât rest until every lab animal in Italy has been released. Last week, they negotiated with police and university faculty that they would leave only on the promise that all 800 of the animals in cages would eventually be released. The negotiators made the promise, and because the activists scrambled the signs that identified which specimen had which disease, the animals will no longer be used in research. But because the animals are unable to live on their own outside the laboratory environment, they will likely be destroyed, and not let go. âYou canât release mutant, diseased mice into the wild,â says Paola Viani, deputy director of the University of Milan pharmacology department. âThat would be truly irresponsible.â