This point bears emphasizing, I think. I suspect that the Republicans want to block Rice because they want Obama to name John Kerry because they believe that Scott Brown can win that seat back. And as I've written before, he probably can, in my admittedly somewhat removed view (but also in the view of certain Bostonians I've consulted on the matter).
McCain and Graham have other motivations: getting a scalp, keeping phony impeachment hopes alive, etc. But let's not forget that these guys are politicians, and senators, and they think of politics and the Senate first. One less Democrat in the Senate would make for a nice little cherry on their sundae.
Which raises another point that deserves attention. If Harry Reid is going to push filibuster reform next January, why should they not include a provision that the minority can't filibuster certain categories of major appointments? The number of vacancies in this administration, judgeships and other key positions, is mind-boggling, and it reached the point where the administration simply stopped trying to fill positions because some wingut senator was placing a hold on every single nomination.
This too needs exposure to the old harsh disinfectant. But if Ayotte really puts a hold on Rice, I spect that'll get lots of attention. Swell move by the party allegedly trying to reach out now to nonwhite voters eh?